Jaundice, fatty liver, cirrhosis and liver transplantation – explained in plain language by Dr. Vibha Varma, liver transplant and HPB surgeon at Lilavati Hospital, Mumbai.

Your liver surgeonDr. Vibha VarmaMBBS, MS, DNB, MRCSEd · Lilavati Hospital, MumbaiPick what you are noticing. Each card says what it commonly means, what cannot wait, and when to see a liver specialist.
Bilirubin is building up in the blood. Common causes are viral hepatitis (A, E or B), alcohol, some medicines or herbal remedies, gallstones or a growth blocking the bile duct, or advanced liver disease.
Go to an emergency department today if jaundice comes with confusion, drowsiness or unusual behaviour, any bleeding or vomiting of blood, high fever with shivering, or if you are pregnant.
Any new jaundice needs liver blood tests and an ultrasound within a few days. Please do not treat it with home or herbal remedies – some of them can worsen liver injury.
Fluid collecting in the abdomen (ascites) and swelling of the feet are common signs that cirrhosis has advanced. Heart or kidney problems can also cause swelling.
Seek care today if the swelling comes with fever or tummy pain (the fluid may be infected), you are passing very little urine, you are breathless, or you are confused.
If you have liver disease and notice swelling for the first time, see a liver specialist soon. It is often the point at which a transplant evaluation should begin.
In liver disease this usually comes from swollen veins (varices) in the food pipe or stomach, caused by high pressure in the liver’s blood vessels. Stomach ulcers can also bleed.
This is always an emergency. Go to the nearest hospital with an endoscopy facility immediately. Do not wait to see if it stops, and avoid painkillers such as ibuprofen.
After the bleeding is controlled, you will need regular follow-up with a liver specialist to prevent it from happening again and to assess the liver.
When the liver cannot clear toxins such as ammonia, they affect the brain (hepatic encephalopathy). Infection, bleeding, constipation, dehydration and sleeping pills are common triggers.
Any new confusion, drowsiness or unusual behaviour in someone with jaundice or liver disease needs emergency care today.
Early signs – sleeping in the day and awake at night, forgetfulness, irritability, a shaking hand – need a prompt review by a liver specialist.
Fat has built up in the liver, usually linked to excess weight, diabetes, high cholesterol or alcohol. It is very common and usually causes no symptoms at first.
Fatty liver on its own is rarely an emergency.
Ask your doctor about liver blood tests and a liver stiffness scan (FibroScan) to check for scarring. Losing 7–10% of body weight, regular activity and no alcohol can reverse it in many people.
Often gallstones. Less commonly a liver cyst or tumour, or a problem in the bile ducts or pancreas – especially with weight loss or loss of appetite.
Go to an emergency department today if pain comes with fever, shivering and yellow eyes (possible bile duct infection), or with repeated vomiting.
Book an ultrasound and a specialist review. Liver, bile duct and pancreas tumours are best assessed by an HPB surgical team.
Bile is not flowing properly into the intestine. Causes include stones or narrowing of the bile ducts, tumours of the bile duct or pancreas, and conditions such as PBC and PSC.
Seek care today if these come with fever or shivering.
Get liver blood tests and an ultrasound promptly, and see a liver specialist with the results.
This guide is general education, not a diagnosis. If you are worried, speak to a doctor. In an emergency, go to the nearest hospital.
Short, direct answers first, with a full article one click away.
Each card opens the full treatment guide on Dr. Varma’s main website, thelivertransplant.in.
Living and deceased donor transplants for adults and children – including emergency transplants for acute liver failure.
Full guide →Liver & bile duct surgeryRemoval of liver tumours, surgery for bile duct problems, gallbladder cancer and complex gallstone disease.
Full guide →Pancreatic surgeryWhipple operation and other surgery for pancreatic tumours, cysts and chronic pancreatitis.
Full guide →Keyhole & robotic surgeryLaparoscopic and robotic techniques for smaller cuts, less pain and faster recovery where suitable.
Full guide →
Consultant & Head, Liver Transplant and Hepato-Pancreato-Biliary Surgery · Lilavati Hospital & Research Centre, Mumbai
Dr. Varma has more than 20 years of experience in living and deceased donor liver transplantation for adults and children, and in complex liver, bile duct and pancreatic surgery. She stays in touch with many of her patients for years after their transplant.
For evaluation of liver disease, liver transplantation – including living donor options – and liver, bile duct and pancreas surgery. Please bring previous reports, scans and a list of current medicines.